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The Green Organic Dutchman and Caliper Foods Report Positive Results from Pharmacokinetic Study of Proprietary Water-Soluble Cannabinoid Technology

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The Green Organic Dutchman Holdings Ltd. (the “Company” or “TGOD”) (TSX:TGOD) (US:TGODF), a leading producer of premium certified organic cannabis, and Caliper Foods (formerly Stillwater Foods), a best-in-class provider of water-soluble cannabinoid products, are pleased to unveil the results of a preliminary human pharmacokinetic (“PK“) study of Caliper CBD, Caliper Foods’ proprietary tasteless and odourless water-soluble powder that can be added to almost any food or beverage.

TGOD intends to commercialize organic cannabinoid dissolvables in Canada beginning in December 2019 under the TGOD-Infusers line of premium cannabis products. The Company has already developed novel fast-acting formulations leveraging this technology with its lineup of organic teas, shots, chewables, and ready-to-drink beverages.  In the US, Caliper Foods plans to release Caliper CBD, its own line of precision-dosed CBD dissolvables, this fall.

For this study, half of the participants were administered 30mg of Caliper Foods’ water-soluble CBD powder in 8oz of water while the other half received 30mg of CBD dispersed in MCT oil. Blood samples were drawn at pre-determined times over six hours.  Early data shows that the group that received Caliper CBD demonstrated faster onset within 15 minutes, with higher concentrations achieved at 15 minutes compared to the maximum concentration achieved at 45 min with the CBD in oil formulation, and a 4.5-fold higher observed total bioavailability. The CBD was largely eliminated from the body after about 6 hours for both Caliper CBD and CBD oil subjects, and a more rapid reduction was observed with the Caliper CBD subjects after 45 minutes.

Following this promising initial study, TGOD and Caliper Foods will shortly conduct a confirmatory Clinical Phase 1A PK study that will test the Caliper CBD technology formulated into TGOD’s planned portfolio of products including beverages, teas, Infusers, and capsules. The study will be conducted in collaboration with a leading US academic institution.

“We are delighted with these PK results as they confirm the enhanced bioavailability and consistent absorption rates of our proprietary ingredient technology, which can infuse both CBD and THC. This study confirms that consumers absorb 4.5 times more CBD with Caliper CBD than with CBD in MCT oil,” commented Keith Woelfel, Director of R&D at Caliper Foods.  “Our R&D team is working closely with TGOD on the next phase of the clinical study, which, if it confirms the PK results in additional product forms, will make Caliper Foods’ and TGOD’s product suites highly differentiated in terms of substantiated quality.”

“We are thrilled with the results of this preliminary PK study which demonstrate the consistency and precision of Caliper Foods’ proven proprietary technology which is already available in Colorado and which TGOD will commercialize in Canada. Based on this early data, Caliper CBD provides a higher and faster absorption level when compared with CBD-infused oil, which opens a number of possibilities for both the medical and adult-use markets.  Patients and consumers are increasingly informed and savvy, and we plan to seize on the market demand for organic CBD and THC-infused products backed by data-driven science and clinical evidence,” commented Dr. Rav Kumar, Chief Science Officer of TGOD. “We are enthusiastically awaiting our Clinical Phase 1A PK results in time for Cannabis 2.0 in Canada.”

Caliper Foods’ technology consists of a suite of zero-calorie, fast-acting, water-soluble solutions that can simply and easily infuse cannabinoids into beverages, food, and other consumer goods.  It is formulated to quickly absorb into the bloodstream with a predictable onset and offset, allowing these products to offer a consistent, controlled, and safe experience.  While cannabinoids are naturally fat-soluble and tend to have a bitter taste, Caliper Foods’ ingredient technology eliminates the need for fat molecules to speed absorption or added sugar to mask the bitterness. As a result, it enables healthier, better-tasting products with no additional fat, sugar, or artificial flavours.

TGOD has an exclusive agreement with Caliper Foods to license the Caliper CBD’s ingredient technology, as well as other proprietary beverage and food technologies and formulations related to cannabinoid-infused consumer packaged goods within Canada and distribute to certain international jurisdictions outside of the United States.

 

SOURCE The Green Organic Dutchman Holdings Ltd.

Cannabis

Sunniva Announces Closing Of Third Tranche Of Short Term Bridge Financing For Proceeds Of Cad $325,000

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Sunniva Inc. (“Sunniva”, the “Company”, “we”, “our” or “us”) (CSE:SNN) (OTCQB:SNNVF), a North American provider of cannabis products and services, is pleased to announce that it has closed the third tranche of the Company’s non-brokered private placement (the “Offering“), previously announced on August 1, 2019 of CAD $325,000 for a total of 325,000 units of the Company (“Units“). In aggregate the total gross proceeds raised by the Offering was CAD $7.57 million and 7.57 million Units issued. Each Unit consists of a principal amount of unsecured promissory notes of the Company (“Promissory Notes“) and common share purchase warrants of the Company (“Warrants“).

As previously disclosed, proceeds of the Offering will be used to provide short term working capital for operations in California, capital costs at the Sunniva California Campus and general corporate purposes.

The Units issued under the Offering have the following terms:

Promissory Notes  

     Maturity: 

6 months from the closing date.

     Interest Rate:

10% (annual rate).

Warrants 

     Number of Warrants:   

0.40 Warrants per Unit (each Warrant entitles the holder to acquire one common

share of the Company at the Warrant Exercise Price).

     Warrant Exercise Price:  

CAD $2.50 per Warrant.

     Warrant Term:         

24 months from closing.

A finder’s fee of 5% payable in cash will be paid to certain investment advisors for introducing certain purchasers of Units to the Company.

The Promissory Notes and Warrants have not been registered under the U.S. Securities Act of 1933, as amended, and may not be offered or sold in the United States absent registration or an applicable exemption from the registration requirements. This press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of the Promissory Notes or Warrants in the United States or in any other jurisdiction in which such offer, solicitation or sale would be unlawful.

For more information please visit: www.sunniva.com.

To be added to the Sunniva email distribution list please register at www.sunniva.com/email-alerts.mailto:

Neither the Canadian Securities Exchange nor its Regulation Services Provider (as that term is defined in the policies of the Canadian Securities Exchange) accepts responsibility for the adequacy or accuracy of this release.

 

SOURCE Sunniva Inc.

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Prairie Records Tops the Charts: Named Top Cannabis Retailer in Canada at Grow UP

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Westleaf Inc. (the “Company” or “Westleaf“) (TSX-V:WL) (OTCQB:WSLFF) is proud to announce its Prairie Records retail stores have been named top cannabis retailer in Canada at the GrowUP Conference & Expo. Singing a different tune in cannabis retail, the award win is a testament to how Prairie Records is offering Canadian’s a truly unprecedented purchasing experience.

“It is extremely gratifying to have Prairie Records be recognized at one of the industry’s largest events and to be able to stand out amongst a field of very worthy retail competitors,” says Adam Coates, Chief Commercial Officer at Westleaf and Retail Brand Strategist for Prairie Records. “We set out to make waves in a sea of sameness by creating an immersive experience like no other in the marketplace, and we are pleased and honoured to receive this, the first Grow UP Conference retail award.”

Ten companies were nominated in the Grow UP retail category at this year’s event, the first for the industry. Among the nominees were independent stores and well-known national chains. Prairie Records was recognized based on delivering an unparalleled consumer purchasing experience and creating a welcoming brand for cannabis consumers.

Westleaf has four Prairie Records stores open, three in the Saskatoon region and one in Calgary, which is hosting its grand opening tomorrow, September 14. The concept combines the tactile and immersive feel of a vinyl record store with a cannabis purchasing experience. Information about the cannabis strains and strengths are presented on album covers and the customer is enveloped in a warm and welcoming retail experience. The staff are well versed on the product offering and provide educational opportunities for both the experienced cannabis connoisseur as well as the novice consumer.

 

SOURCE Westleaf Inc.

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Cannabis

INTERCURE: CANNDOC signs strategic distribution agreement with S.L.E. of TEVA Pharmaceuticals

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InterCure (TASE: INCR), announced that subsidiary Canndoc has entered into a strategic distribution agreement with Salomon, Levin, Elstein (S.L.E.,) which is owned by Teva Pharmaceuticals Industries (NYSE: and TASE: TEVA).

Under terms of the agreement, S.L.E. will distribute Canndoc’s GMP products to pharma clients, including hospitals, health maintenance organizations (HMOs) and all pharmacies in Israel, including pharmacy chains. In the future, as regulatory approvals allow, S.L.E. will provide logistics capability for exporting Canndoc’s products to countries that support regulations for the sale and distribution of cannabis products for medical use.

S.L.E. is one of Israel’s leading companies for providing health logistics services and distributes products from dozens of local and international companies. S.L.E. is licensed by the Israeli Ministry of Health, and also holds a GDP distribution license.

“Our agreement with S.L.E., Israel’s leading company in distributing medical products, creates a complete supporting platform for supplying Canndoc’s GMP products to any location in Israel and for countries with similar regulations,” said Canndoc’s Chairman Ehud BarakThrough its S.L.E. partnership, Canndoc has aligned itself with one of the most prominent pharmaceutical companies in the world, for the distribution of cannabis-based medical treatments to countries that recognize the value of these medicines for people in need.”

S.L.E. CEO Aviad Bossi adds, “The agreement brings together our well-established pharmaceutical distribution network with Canndoc’s high quality medical cannabis industry presence and market leadership. Beyond the operations in Israel, this agreement will provide Canndoc significant logistical capabilities that can support Canndoc’s exporting operations from Israel.”

The distribution agreement is set for a 3-year term and includes a mechanism for automatic extension periods of two years each.

Canndoc is one of the first licensed producers, with its GMP-approved medical cannabis Rx products being sold in pharmacies. The engagement in this distribution agreement will broaden Canndoc’s ability to distribute GMP products to its patients within the S.L.E. pharmacy network throughout Israel. In addition, S.L.E. will provide Canndoc significant logistical capabilities in the future supporting Canndoc’s ability to export its products to countries with consistent regulation for the sale and distribution of cannabis products for medical use.

 

SOURCE Canndoc

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